Inbred cannibals are set menace the woods of West Virginia again as director Declan O'Brien prepares "Wrong Turn 3" for a DVD and Blu-Ray release this fall.

The Fox Home Entertainment sequel picks up where Joe Lynch's "Wrong Turn 2" concluded, and O'Brien is seeking to take the franchise in a new and intense direction.

"This 'Wrong Turn,' when it was being developed, the first movie was beautiful people in the woods getting hunted down and getting killed and eaten by cannibal hillbillies," O'Brien said in an interview with ShockTillYouDrop.com. "The second movie was beautiful people in a reality show getting hunted down and eaten by cannibal hillbillies. You can't do that a third time. Where's the sport in that?

"We wanted to take the franchise in a direction where the cannibal hillbillies are up against people who fight back. It becomes a 'Battle Royale' and, basically, you've got a prison bus filled with the worst murderers in the country being transferred to a high security prison in West Virginia. Of course, they escape and fall into the hands of Three Finger and the cannibal hillbillies and it becomes a battle. It starts at three o'clock in the afternoon and finishes at dawn. So it's all real time and once it gets going, it grabs you by the throat and doesn't let go."

With prisoners on the loose, the conflict in "Wrong Turn 3" creates a film reflective of other genres.

"This is a lot more action oriented," he explained. "There is horror and gore throughout, but there are some awesome fights and I roll a city bus, just like 'The Fugitive.' And that ain't an easy task without killing anyone for real. There were a couple of films this is inspired by. One is 'The Treasure of the Sierra Madre.' The other is that this is like 'Con Air' meets 'Wrong Turn.'"

The collision of cannibals and convicts presented a distinct opportunity for O'Brien to showcase some serious splatter.

"The bar was set pretty high by Rob Schmidt and Joe Lynch, they're really inventive, and I knew the fans would expect nothing less than some more sick shit. I think we delivered in a pretty large way."

The first look at the "Wrong Turn 3 "trailer is expected today at Fangoria's Weekend of Horrors in Los Angeles.